3-氯咪唑并[1,2-a]嘧啶 - Names and Identifiers
3-氯咪唑并[1,2-a]嘧啶 - Physico-chemical Properties
Molecular Formula | C6H4ClN3
|
Molar Mass | 153.57 |
Density | 1.51±0.1 g/cm3(Predicted) |
pKa | 2.70±0.30(Predicted) |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD09994773 |
3-氯咪唑并[1,2-a]嘧啶 - Risk and Safety
Hazard Symbols | T - Toxic
|
Risk Codes | R25 - Toxic if swallowed
R43 - May cause sensitization by skin contact
|
Safety Description | S36/37 - Wear suitable protective clothing and gloves.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
|
Hazard Class | IRRITANT |
3-氯咪唑并[1,2-a]嘧啶 - Introduction
3-Chloroimidazo[1,2-a]pyrimidine is an organic compound with the chemical formula C6H3ClN4. It is a white crystal with low solubility. The following is a description of the nature, use, preparation and safety information of 3-Chloroimidazo[1,2-a]pyrimidine:
Nature:
1. Appearance: white crystal
2. molecular weight: 162.57g/mol
3. Melting point: 114-116°C
4. Boiling point: 344°C
5. density: 1.58 g/cm
6. Solubility: 3-Chloroimidazo[1,2-a]pyrimidine has low solubility in water, but has good solubility in organic solvents (such as dimethyl sulfoxide, dimethyl formamide, etc.).
Use:
1. Chemical synthesis: 3-Chloroimidazo[1,2-a]pyrimidine can be used as an organic synthesis intermediate for the synthesis of other compounds, such as drugs, pesticides, etc.
2. Drug research: It is used to synthesize biologically active compounds, such as anti-cancer drugs, antibacterial drugs, etc. It is also widely used in drug research.
Preparation Method:
The preparation of 3-Chloroimidazo[1,2-a]pyrimidine can be achieved by various methods, for example by reacting 2-chloroimidazo [1,2-a]pyrimidine with chloroacetic acid. The specific preparation method needs to be selected and optimized according to actual needs and conditions.
Safety Information:
1. 3-Chloroimidazo[1,2-a]pyrimidine should avoid prolonged contact with the skin and inhalation of its dust or gas, and avoid direct exposure to the sun.
2. When handling the compound, wear personal protective equipment such as protective glasses, gloves and protective mask.
3. may cause harm to the environment, can not be discharged into the natural environment.
4. When using or handling the compound, strictly follow the operating procedures and safe operating guidelines, and proceed under well-ventilated conditions.
5. 3-Chloroimidazo[1,2-a]pyrimidine should be properly stored and disposed of to prevent fire or other safety incidents.
Last Update:2024-04-09 02:00:56